Posts in Case Study
Validation Master Planning for a State of The Art Sterile Manufacturing Facility

Problem Definition

A large pharmaceutical conglomerate was establishing a brand new, state of the art sterile manufacturing plant.  The facility design had to comply with the requirements of the United States Food and Drug Administration (FDA), the Japanese Ministry of Health and Welfare (JMHW) and the European Agency for the Evaluation of Medical Products (EMEA).  However, the effort had the following major stumbling blocks....

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Validation of a GLP Laboratory

Problem Definition

A GLP laboratory within a large research establishment comprised of several laboratory systems that are used in GLP studies.  This project involved development of a master plan and the compliance infrastructure for the entire GLP organization.  It also involved development and implementation of life cycle deliverables for several laboratory systems. The validation effort had the following major stumbling blocks.....

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IT Infrastructure and Network Qualification Case Study

Problem Definition

A company, with several facilities across multiple continents, was looking to qualify their network infrastructure. The qualification effort was underway for over six months prior to ValiMation’s involvement, and the project going nowhere fast.  The qualification effort had the following stumbling blocks....

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ABACUS – Accelerating Business Automation and Compliance Using Software

Software Integration and Qualification of an MS SharePoint based knowledge management infrastructure for a large Pharmaceutical Manufacturing Facility. The system provides web based workflow, collaboration features and an electronic repository for electronic documents / files for various departments within the facility. This includes equipment/hardware/software manuals, validation documentation, CAD drawings, PLC programs, packaging documentation, batch records, stability reports, etc..  The solution incorporated ValiMation’s Application Implementation Methodology (AIM) for rapid deployment.

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Validation of a BPCS ERP System in a Sterile Manufacturing Facility Using a Scientific Approach

Problem Definition

A particular sterile manufacturing company was using BPCS as an ERP system for over 10 years. However, the system was not validated and the company was using manual processes and manual documentation to meet many compliance needs.  They were mandated to validate their ERP system by the EMEA....

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